I just read the article "Understanding Biofilms" autor Amy Proal. In my opinion this is outstanding job and all mp members should read this http://bacteriality.com/2008/05/26/biofilm/. "But in the case of low, pulsed dosing, where an antibiotic is administered, withdrawn, then administered again, the first application of antibiotic will eradicate the bulk of biofilm cells, leaving persister cells behind. Withdrawl of the antibiotic allows the persister population to start growing. Since administration of the antibiotic is temporarily stopped, the survival of is not enhanced. This causes the persister cells to lose their phenotype (their shape and biochemical properties), meaning that they are unable to switch back into biofilm mode. A second application of the antibiotic should then completely eliminate the persister cells, which are still in planktonic mode"
This paragraph explain how MP kills persisters in biofilm mode. My question is: Is thebiofilm the only cause antibiotic resistance? And if it's not, how MP kills other persisters? From the beginning of my Lyme sickness I took huge amount of antibiotics orally and IV(including antibiotics that recommended in MP) with no effect. Is it possible that I developed resistance that can not be destroyed even by MP .
Thank You
Gene
____________________ Lyme 05 125D51 25D40(Aug07) Ph1 Feb08 NoIRs low lux home & work covered up on commute 25D19.3(May08) Ph2May08
Gene, it is more possible that the antibiotics you took were totally ineffective against the organisms making you ill. Every antibiotic is different, and their action also changes with dose and frequency of administration. The books won't tell you that, you will need to delve into the journal articles to find it.
Don't worry about antibiotic resistance. The immune system doesn't just use one family of antimicrobials - it has at least 24 which have been identified so far The key is to get the immune system operational again, and that is what the MP does.
